J Neuroimmunol. 2016 Feb 15;291:70-2. doi: 10.1016/j.jneuroim.2015.12.014. Epub 2015 Dec 31. Forwell AL1, Bernales CQ1, Ross JP1, Yee IM1, Encarnacion M1, Lee JD1, Sadovnick AD2,…
Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Varrin-Doyer M, Spencer CM, Schulze-Topphoff U, Nelson PA, Stroud RM, C Cree BA, Zamvil SS.
About APTA ? The American Physical Therapy Association (APTA) is a national professional organization representing more than 74,000 members.
Rituximab is increasingly used for prevention of relapses of neuromyelitis optica (NMO), a condition that is highly associated with serum anti-aquaporin-4 (AQP4) antibodies. However, B-cell depletion also induces systemic B-cell activating factor (BAFF), which may promote antibody production. We collected serial serum samples from a total of seven patients with NMO prior to, and following, treatment with rituximab
INTRODUCTION: Optic neuromyelitis or Devic’s syndrome is a very rare disease affecting the optic tracts and the spinal cord. Its association with evolving pulmonary tuberculosis has been reported in a handful of case reports.
Background: Association of the haplotype including DRB1*1501 with multiple sclerosis (MS) is well established. Recent studies have suggested lack of association of this haplotype with neuromyelitis optica (NMO) (Z?phir et al