Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis. Sinnecker T, Dörr J, Pfueller CF, Harms L, Ruprecht K, Jarius S, Brück W, Niendorf T, Wuerfel J, Paul F. Source From the NeuroCure Clinical Research Center (T.S., J.D., C.F.P., J.W., F.P.), Clinical and Experimental Multiple Sclerosis Research Center (J.D., C.F.P., L.H., K.R., F.P.), and Department of Neurology (L.H., K.R.), Charité-Universitaetsmedizin Berlin, Berlin; Division of Molecular Neuroimmunology, Department of Neurology (S.J.), University of Heidelberg, Heidelberg; Department of Neuropathology (W.B.), University Medical Center Göttingen, Göttingen; Berlin Ultrahigh Field Facility (T.N., J.W.), Max Delbrueck Center for Molecular Medicine, Berlin; Institute of Neuroradiology (J.W.), University of Luebeck, Luebeck; and Experimental and Clinical Research Center (T.N., F.P.), Charité-Universitaetsmedizin Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany
Association Between Paroxysmal Tonic Spasms and Neuromyelitis Optica Nida Usmani, MD; Gurdesh Bedi, MD; Byron L. Lam, MD; William A
Pain in neuromyelitis optica and its effect on quality of life A cross-sectional study Y. Kanamori , PhD , I.
Wise Young, Ph.D., M.D. W
Neuromyelitis optica (NMO) is an inflammatory/demyelinating disorder predominantly affecting the optic nerves and spinal cord. Recent findings showed an underlying humoral abnormality in NMO, characterized by a serum antibody against aquaporin-4 (Aqp-4-Ab). In this study, we evaluated the Aqp-4-Ab status among Turkish patients with NMO to determine the clinical and prognostic relevance
Background: Association of the haplotype including DRB1*1501 with multiple sclerosis (MS) is well established. Recent studies have suggested lack of association of this haplotype with neuromyelitis optica (NMO) (Z?phir et al
Neuromyelitis optica (NMO) is an autoimmune disease of the central nervous system characterized by severe demyelinating inflammatory attacks typically affecting the spinal cord and optic nerves. Anti-aquaporin-4(AQP4) serum autoantibodies are present in approximately 70% of NMO patients. Those antibodies probably are pathogenic and the titers are elevated during relapse as compared with those in remission