Association of Neuromyelitis Optica With Severe and Intractable Pain. Qian P, Lancia S, Alvarez E, Klawiter EC, Cross AH, Naismith RT. Abstract OBJECTIVE To contrast differences in pain and treatment outcomes between neuromyelitis optica (NMO) and multiple sclerosis (MS)
Aquaporin-4 Antibodies Are Not Related to HTLV-1 Associated Myelopathy.
Several risks are involved with placement of baclofen pumps.
Varieties of autoantibodies are known to relate to autoimmune neurological disorders as the diagnostic and therapeutic markers. Some of them affected directly to the pathomechanisms of neurological diseases
Introduction: Recurrent NMO is an idiopathic inflammatory demyelinating disease of the CNS that preferentially affects the optical nerve and spinal cord. Only recently some studies reported RNMO in pediatric population. Objective: describe the clinical course of pediatric patients diagnosed with RNMO
In a subgroup of patients with neuromyelitis optica (NMO), a severe inflammatory demyelinating disorder of autoimmune origin characterized by recurrent attacks of optic neuritis and longitudinally extensive transverse myelitis, a parainfectious pathogenesis may play a central role.
We systematically evaluated the frequency of neurological disorders and muscle and neural autoantibodies in 177 patients with neuromyelitis optica (NMO) and in 250 control subjects (173 healthy; 77 multiple sclerosis, MS, patients). An excess of myasthenia gravis (MG, 2%), and muscle-type acetylcholine receptor antibody (11%) was detected among NMO patients. The presence of neural or muscle autoantibodies was more common in NMO patients (34%) than in MS patients or healthy controls (7%), P less than 0.0001