Abstract Neuromyelitis optica is an autoimmune disorder characterized by optic neuritis, transverse myelitis, and aquaporin-4 autoantibodies.
Sexual dysfunction in patients with neurologic disorders ? Contributors Jasvinder Chawla MD MBA , author. Dr. Chawla of Loyola University Medical Center and Hines VA Hospital has no relevant financial relationships to disclose
Overview Management of voiding dysfunction in neurologic disorders can substantially improve the quality of life as well as the health of patients. A systematic review of the pattern of voiding dysfunction leads to an understanding of the underlying mechanism, which, in turn, allows the treating physician to develop a strategy for managing it. Neurourology, although a relatively new field of study, has revolutionized the management of a vexing problem that affects millions of patients.
We describe two patients with recurrent longitudinally extensive transverse myelitis (LETM) associated with human T-lymphotropic virus type I or II (HTLV-I/II) exposure, and with neuromyelitis optica (NMO) immunoglobulin G (IgG) antibody in one case. HTLV-I/II are well known retroviral agents of myelopathy and B-cell dysfunction in humans.
Neuromyelitis optica (NMO) has been reported to be associated with endocrinopathies, such as amenorrhea, galactorrhea, and diabetes mellitus. However, its association with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is extremely rare.
Background: The burden of multiple sclerosis (MS) includes fatigue, depression and worsening of health-related quality of life (HRQOL).