Objectives: the aim of our study was to investigate whether the presence of IgG-NMO antibody is associated with a different pattern of response at visual evoked potentials (VEPs) in patients affected by neuromyelites optica spectrum of disorders (NMOsd) with optic neuritis (ON). Methods: we retrospectively studied clinical, immunological and neurophysiological data from 28 patients affected by NMOsd who presented at least one optic neuritis (16 patients bilateral and 12 unilateral).
Background: Although it has been well established that vaccination does not increase the risk of relapse in patients with multiple sclerosis (MS), no study on the influence of immunization on neuromyelitis optica spectrum disorder (NMOsd) has been conducted. As NMO differs from MS in a number of aspects, including its immunopathogenetic mechanisms, vaccination may have some influence on the occurrence of new relapses
Optic neuritis is defined as inflammation of the optic nerve.
Sir, We report a 9-yr-old girl with a severe relapsing–remitting course of neuromyelitis optica (NMO) [who had a dramatic and -sustained improvement over a 2-yr period of treatment with mycophenolate mofetil (MMF), the prodrug of mycophenolic acid. A 9-yr-old Caucasian girl, previously healthy, was admitted to A.