Neuromyelitis Optica: An Antibody-Mediated Disorder of the Central Nervous System Jiwon Oh and Michael Levy Department of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Pathology 509, Baltimore, MD 21287, USA Received 7 July 2011; Revised 4 October 2011; Accepted 13 October 2011 Academic Editor: Philippe Cabre Copyright ? 2012 Jiwon Oh and Michael Levy
Beneficial Plasma Exchange Response in Central Nervous System Inflammatory Demyelination Setty M. Maga?a, BS; B.
OBJECTIVE: To investigate the clinical relevance of memory Th17 cells in patients with neuromyelitis optica (NMO) or multiple sclerosis (MS). PATIENTS AND METHODS: The proportion of peripheral memory Th17 cells was determined by flow cytometry. Sera IL-17A and IL-23 levels were detected by ELISA kits
Background: Acute transverse myelitis (ATM) in patients with no history of central nervous system (CNS) demyelinating disease may be idiopathic or herald the development of neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). NMOSD may differ from MS in pathogenesis, prognosis and response to treatment, and radiological features at the first presentation of ATM that distinguish between NMOSD and MS would be desirable
OBJECTIVE: To investigate the differential diagnostic value of NMO-IgG for neuromyelitis optica (NMO) versus multiple sclerosis (MS) and to analyze its possible clinical features related to NMO-IgG. METHODS: Forty-one NMO patients and 44 MS patients in acute phase and 40 healthy controls were investigated. Serum NMO-IgG was tested by indirect immunofluorescence assay.
Background: Although brain lesions are now recognized more frequently in neuromyelitis optica spectrum disorder (NMOSD), most of them have been reported to be nonspecific and rarely symptomatic.
OBJECTIVE: In the present study, we examined some demographic and clinical features of Turkish LDDD patients and we compared these features with Turkish conventional MS patients, on the basis of demographic, clinical and immunological features. BACKGROUND: So called limited disseminated demyelinating diseases (LDDDs) includes optic neuritis (ON), transverse myelitis (TM), optic-spinal multiple sclerosis (OSMS) and neuromyelitis optica (NMO). OSMS and NMO select the involvement of optic nerve and spinal cord more than conventional multiple sclerosis (CMS)
Background and Objective: Our objective was to characterize the clinical and radiologic features of Korean pediatric patients with relapsing central nervous system (CNS) demyelination disease.