Rituximab dosing and monitoring strategies in neuromyelitis optica patients: creating strategies for therapeutic success Benjamin M Greenberg Donna Graves Gina Remington Paula Hardeman Martha Mann Nitin Karandikar Olaf Stuve Nancy Monson Elliot Frohman University of Texas Southwestern Medical Center, Dallas, TX, USA Benjamin M. Greenberg, MD, MHS, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8806, USA. Email: benjamin.greenberg@utsouthwestern.edu Abstract Background: Neuromyelitis optica (NMO) is an autoimmune condition that predominantly causes severe optic neuritis and transverse myelitis.
WHILE HER COLLEAGUES ARE COUNTING DOWN THE DAYS, Rebecca Alves is one kindergarten teacher dreading the end of the school year. She suffers from a rare autoimmune disorder called Devic’s disease and has been told by her insurer that on July 1 it will stop paying for the $12,000-a-month infusions she’s been taking for seven years.
Bowel retraining URL of this page: http://www.nlm.nih.gov/medlineplus/ency/article/003971.htm A program of bowel retraining, Kegel exercises , or biofeedback therapy may be used by people with: Fecal incontinence Nerve problems (such as from multiple sclerosis or other conditions) Severe constipation The bowel program has several steps that help with regular bowel movements. Within a few weeks of beginning a bowel program, most people can have regular bowel movements. Before starting a bowel training program, get a thorough physical examination.
Medications Nerve pain is hard to treat. Treatment usually helps but often does not relieve all of your pain
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Quantification of retinal neural loss in patients with neuromyelitis optica and multiple sclerosis with or without optic neuritis using optical coherence tomography Mario L.R. Monteiro 1, Danilo B
Koji Shinoda Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Takuya Matsushita Department of Clinical Neuroimmunology, Graduate School of Medical Sciences, Kyushu University, Japan Konosuke Furuta Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Noriko Isobe Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Tomomi Yonekawa Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Yasumasa Ohyagi Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Jun-ichi Kira kira@neuro.med.kyushu-u.ac.jp Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan Abstract This report describes, for the first time, an occurrence of wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) in a 19-year-old female with neuromyelitis optica (NMO) spectrum disorder, who had anti-aquaporin-4 (AQP4) antibody. A high signal intensity lesion on T2-weighted MRI was detected in the midbrain tegmentum adjacent to the aqueduct, and presumably involved the medial longitudinal fasciculus bilaterally at the caudal levels. Plasma exchange resolved both WEBINO syndrome and the midbrain lesion
BACKGROUND: Few data exist on a possible benign form of neuromyelitis optica (NMO). OBJECTIVES: To identify NMO with a good outcome (go-NMO) among a large population of patients and to describe demographic and clinical variables associated with go-NMO vs standard NMO and benign multiple sclerosis.
The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion. This coordinated activity is regulated by the central and peripheral nervous systems.