Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Tradtrantip L , Zhang H , Saadoun S , Phuan PW , Lam C , Papadopoulos MC , Bennett JL , Verkman AS . Source Departments of Medicine and Physiology, University of California, San Francisco, CA
Anti–Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica Lukmanee Tradtrantip PhD 1 , Hua Zhang PhD 1 , Samira Saadoun PhD 2 , Puay-Wah Phuan PhD 1 , Chiwah Lam BS 3 , Marios C.
BACKGROUND: Antibodies to aquaporin-4 (AQP4) are found in a fraction of Japanese opticospinal multiple sclerosis (OSMS) patients. However, it remains unknown whether anti-AQP4 antibody-positive and negative OSMS patients possess an identical disease