Brain Involvement in Neuromyelitis Optica Spectrum Disorders Koon Ho Chan, MD, FRCP; C. T. Tse, MBBS, MRCP; C.
Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disease often associated with a highly specific autoantibody, aquaporin-4 antibody.
BACKGROUND: Few data exist on a possible benign form of neuromyelitis optica (NMO). OBJECTIVES: To identify NMO with a good outcome (go-NMO) among a large population of patients and to describe demographic and clinical variables associated with go-NMO vs standard NMO and benign multiple sclerosis.
A 29-YEAR-OLD WOMAN of Afro-Caribbean descent with a history of thyrotoxicosis was evaluated for right leg weakness and diagnosed as having myelitis.