Cerebrospinal Fluid BAFF and APRIL Levels in Neuromyelitis Optica and Multiple Sclerosis Patients During Relapse. Wang H, Wang K, Zhong X, Qiu W, Dai Y, Wu A, Hu X. Source Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Sexual problems associated with neurological diseases (Neurosexology) European Federation of Neurological Societies Task Force on Neurosexology*. ? Lundberg PO Swash M, Vodusek D B ? Correspondence to P O Lundberg Department of Neuroscience: Neurology University Hospital Uppsala SE-751 85 Sweden Tel + 46 18 611 50 26 Fax + 46 18 611 50 27 E-mail: PO.Lundberg@neurologi.uu.se ? ? *The following text is based on Guidelines for Neurologists about Sexual problems associated with neurological diseases (Neurosexology) compiled by the members of the European Federation of Neurological Societies Task Force on Neurosexology published in 2001.
In neuromyelitis optica (NMO), B-cell autoimmunity to aquaporin-4 (AQP4) has been shown to be essential. However, the role of T cells remains ambiguous
BACKGROUND: They are severe inflammatory demyelinating diseases of the central nervous system, often called idiopathic inflammatory demyelinating disease (IIDD). These diseases are explosive or pseudotumoral multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), transverse myelitis and neuromyelitis optica (NMO).
BACKGROUND: Under the therapeutic point of view, neuromyelitis optica (NMO) poses major challenges. Patients with NMO manifest severe disability from recurrent demyelinating lesions and the therapies are only partially effective. We performed a retrospective analysis of the records of patients followed at our institution and provide suggestions for management of acute relapses and preventive therapy.
Objective: Movement disorders (MD) have been described in demyelinating diseases, especially in multiple sclerosis (MS). Paroxysmal dystonia, also called tonic spasm (TS) is the most frequent MD in MS. Only few cases have been reported in Neuromyelitis optica (NMO) albeit it’s frequently referred by these patients
Neuromyelitis optica (NMO; Devic’s disease) and the NMO spectrum disorders are idiopathic inflammatory demyelinating disorders that affect the central nervous system and have a predilection for optic nerves and spinal cord. The identification of NMO-IgG as a disease-specific marker and aquaporin 4 as the target antigen has renewed interest in NMO.