Background and Objective: Our objective was to characterize the clinical and radiologic features of Korean pediatric patients with relapsing central nervous system (CNS) demyelination disease.
Devic’s Neuromyelitis Optica (NMO) is an idiopathic, inflammatory, demyelinating disease specific to the spinal cord and optic nerves resulting in acute, severe myelitis and optic neuritis. Unlike “typical” Multiple Sclerosis (MS), the brain is characteristically spared and spinal cord involvement spans at least three vertebral segments. NMO is often misdiagnosed as MS; however, recent research has identified distinguishing pathophysiologic, clinical, neuroimaging, and autoantibody criteria favoring a distinct disease