Mult Scler. 2012 Aug 30. [Epub ahead of print] Elsone L, Townsend T, Mutch K, Das K, Boggild M, Nurmikko T, Jacob A. Source The…
Atypical presentations of neuromyelitis optica Douglas SatoI, II; Kazuo FujiharaIII IDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan IIDepartment of Neurology, Faculty of Medicine – University of São Paulo, São Paulo SP, Brazil IIIDepartment of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan Neuromyelitis optica (NMO) or Devic’s disease is an inflammatory disease of central nervous system classically characterized by acute, severe episodes of optic neuritis (ON) and longitudinally extensive transverse myelitis (TM)1. The article published in 1894 by Dr Eugène Devic was based on a 45-years old female patient presenting with bilateral ON followed by TM and she deceased about a month after the monophasic opticomyelitis2.
Lidocaine unmasks silent symptoms and eases neuropathic pain in multiple sclerosis patients; however, the effects of lidocaine in neuromyelitis optica have never been reported. We describe the case of a 59-year-old Japanese woman with neuromyelitis optica spectrum disorder who developed optic neuritis 1 day after intravenous lidocaine injection for treating allodynia. Her symptom seemed to result from a relapse of neuromyelitis optica induced by lidocaine administration, and not because of the transient effects of intravenous lidocaine administration.