Neuromyelitis optica following thymectomy with severe spinal cord atrophy after frequent relapses for 30 years]. [Article in Japanese] Hironishi M, Ishimoto S, Sawanishi T, Miwa H, Kawachi I, Kondo T. Source Department of Internal Medicine, Seishokai Kasei-Tamura Hospital.
WHILE HER COLLEAGUES ARE COUNTING DOWN THE DAYS, Rebecca Alves is one kindergarten teacher dreading the end of the school year. She suffers from a rare autoimmune disorder called Devic’s disease and has been told by her insurer that on July 1 it will stop paying for the $12,000-a-month infusions she’s been taking for seven years.
Take Acton & Make Some Noise In 24 days, on May 6, I will run the Pittsburgh half marathon: 13.1 miles of celebrating life. A year ago, to be specific it was ten months ago, it was unimaginable that I would be strong enough to take a long walk. The thought of running at all…anywhere…wasn’t even a consideration for me.
Abstract Neuromyelitis Optica (NMO) is a rare neuroinflammatory disorder with limited epidemiological data. Antibodies against aquaporin-4 (Aq4ab) are reported to be highly specific for NMO and NMO spectrum disorders (NMO-SD).
Neuromyelitis optica (NMO) is an inflammatory demyelinating disorder characterized by optic neuritis and acute myelitis. A parainfectious pathogenesis may play a partial role in the development of this disorder.
Background: Neuromyelitis Optica (NMO) is a rare but severe disease affecting young adults with a mean age at onset of 34.5 years. The female: male ratio is 3:1 so most of patients are women of childbearing potential.
Background: Acute transverse myelitis (ATM) in patients with no history of central nervous system (CNS) demyelinating disease may be idiopathic or herald the development of neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). NMOSD may differ from MS in pathogenesis, prognosis and response to treatment, and radiological features at the first presentation of ATM that distinguish between NMOSD and MS would be desirable
Current diagnostic criteria of neuromyelitis optica (NMO) includes presence of acute optic neuritis (ON) and myelitis with at least two of the three supportive criteria, which consist of spinal cord magnetic resonance image (MRI) lesion extending over 3 vertebral segments, brain MRI lesion, which does not meet the diagnostic criteria for multiple sclerosis, and NMO-IgG seropositive status A 34-year-old woman presented with two episodes of acute demyelinating processes in the central nervous system within three years. Firstly, she presented with a 2-week history of neck pain, oscillopsia, vertigo, and weakness
We report a 25-year-old woman who developed optic neuritis and encephalomyelitis following primary Sjogren’s syndrome (SjS).
We report the case of a 60-year-old woman with myasthenia gravis (MG) and Basedow’s disease who seven years after thymectomy developed subacute myelitis, a limited form of neuromyelitis optica (NMO). The patient presented with a centrally located long spinal cord lesion (LCL) on cervical cord MRI, anti-aquaporin 4 (AQP4) antibody in serum, and HLA DPB1*0501
BACKGROUND: Few data exist on a possible benign form of neuromyelitis optica (NMO). OBJECTIVES: To identify NMO with a good outcome (go-NMO) among a large population of patients and to describe demographic and clinical variables associated with go-NMO vs standard NMO and benign multiple sclerosis.
Background: Neuromyelitis optica (NMO) is a severe demyelinating disease often leading to serious disability. Accumulating evidence now implicates humoral mechanisms in its pathogenesis.